UroproMAX male®

1. Elimination of pathogens (mechanical elimination and biofilm disruption)
2. Regeneration and protection of the urothelium
3. Maintenance and regeneration of the microbiota
4. Prevention of relapse and functional support

Composition:

• D-mannose
• N-acetyl cysteine
• Chondroitin sulfate
• Go-Less® Men – patented formulation (EFLA 940)
• Ashwagandha KSM-66®
• Carefully selected probiotic cultures essential for men's urinary health (Lactobacillus plantarum LB931 and Synbio®complex (L.rhamnosus, L.paracasei))

Used in cases of:

• Acute and chronic urinary tract infections (UTIs)
• Prevention of infections during catheter use and after urological procedures
• Recovery after antibiotic therapy
• Symptoms of overactive bladder
• Chronic prostatitis and bladder pain syndrome
• Prevention of recurrent infections and mucosal dysfunctions of the urinary tract, bladder, and prostate

Directions for use:

• For prophylaxis and in cases of acute infections (as an adjunct to antibiotic therapy), take for at least 10 days, with a minimum interval of 2 hours between this product and antibiotic intake.
• In cases of recurrent/chronic infections, catheter use, and chronic bladder and/or prostate conditions, take for 6–12 weeks to achieve the expected results.

Recommendation: Take the product before bedtime, on an empty bladder.
Pour the contents of one sachet into a glass, then gradually add 200 ml of water while stirring until the powder is completely dissolved. Consume immediately after preparation.

Warning:

Do not exceed the recommended daily dose.
Do not use the product in case of hypersensitivity to any of its ingredients.
The product contains polyols – excessive consumption may have a laxative effect.
Individuals undergoing drug therapy should consult a physician before use.
In the event of adverse effects, discontinue use and consult a physician.

Packaging:

10 sachets, powder for oral use, tropical fruit flavor

Mechanisms of action:

D-mannose – Mechanical elimination of bacteria

D-mannose is a simple sugar that is readily absorbed in the upper part of the gastrointestinal tract and quickly excreted through urine. This natural monosaccharide is found in fruits such as blueberries and cranberries. It does not affect blood glucose levels and is rapidly eliminated via the kidneys.

Mechanism:
By binding to type 1 bacterial fimbriae (particularly E. coli – the main cause of urinary tract infections, responsible for up to 90% of cases) that are sensitive to mannose, it prevents their adhesion to bladder cells. The bacteria are then naturally eliminated through urine.

Result:
Instead of remaining in the urinary tract, the bacteria are naturally eliminated through urination.

Acetyl cysteine (NAC) – Bacterial biofilm disruption

A cysteine amino acid derivative with strong antioxidant and mucolytic properties. It breaks down bacterial biofilm, which protects pathogens from the immune system and antibiotics. Biofilm is a key mechanism in chronic and resistant infections – by removing this protective layer, bacteria become more vulnerable to the immune response and antibiotics.

• Increases drug penetration and reduces inflammation and oxidative stress
• NAC is one of the few ingredients with synergistic effects in anti-infective therapy – it enhances the effect of antibiotics and supports mucosal recovery

Chondroitin sulfate – Regeneration of the urothelial barrier

The bladder mucosa contains a glycosaminoglycan (GAG) layer that acts as a natural barrier against bacteria and urinary irritants. Chondroitin sulfate is a key structural component of this GAG layer. In the case of infections, this layer is degraded, allowing bacteria to penetrate tissues more easily and leading to symptoms such as pain, burning, and frequent urination. It helps in conditions such as bladder pain syndrome, as well as in men with chronic inflammation and sensitive mucosa.

Mechanism:
It restores the damaged mucosa, thereby reducing pain, irritation, and frequent urination. It is beneficial in interstitial cystitis and prostatitis.

Go-Less® Men patented formula (EFLA® 940) - Reduction of frequent urination and urgency

A patented pumpkin seed (Cucurbita pepo) extract standardized for sterols and lignans is a unique herbal ingredient for managing functional urinary tract conditions in men, without affecting sexual function.

It acts on alpha-adrenergic receptors in the bladder muscles, thereby:

• Reducing the sensation of urgency,
• Improving urinary control,
• Reducing the frequency of nighttime urination (nocturia)
• Reducing urgency and nighttime frequency without hormonal effects

Ashwagandha KSM-66® - Patented adaptogen

An adaptogenic plant from traditional medicine, known for its immunomodulatory and anti-stress effects, which helps the body cope with physiological and emotional stress that may act as a trigger for recurrent infections.

Mechanism:

It reduces stress that contributes to urological symptoms, balances cortisol levels, and improves sleep and local immunity:

• Reduces cortisol levels,
• Improves mucosal immunity,
• Contributes to better sleep and reduced tension.
• Urological symptoms are often aggravated by stress – Ashwagandha helps break the cycle of anxiety, tension, and urinary discomfort

Probiotics (L. plantarum, L. paracasei, L. rhamnosus) – urinary microbiota

Mechanism of action Lactobacillus plantarum and Synbio® complex:

• Maintain acidic pH
• Reduce adhesion of pathogenic bacteria
• Restore microbiota after antibiotic therapy. This is particularly important for men who are frequently on antibiotics – preventing dysbiosis and secondary infections.

Lactobacillus plantarum LB931 (2 billion colony-forming units) – Microbiome restoration

L.plantarum is a robust, facultative anaerobic strain that naturally inhabits the intestines but shows the ability to temporarily colonize the urogenital tract. It is a probiotic strain capable of colonizing both the gastrointestinal and urogenital tracts.

Mechanism of action:

• Inhibits adhesion of pathogenic bacteria (especially E. coli)
• Produces bacteriocins and H2O2 that destroy pathogens
• Reduces biofilm formation and inflammation
• Modulates the immune response (IL-10↑, TNF-α↓)
• Supports restoration of the gut-prostate axis

Synbio® complex = Lactobacillus rhamnosus IMC501 + Lactobacillus paracasei IMC502) (1 billion colony-forming units) – Microbiome restoration

A synbiotic formulation of L.rhamnosus and L.paracasei
Mechanism of action:

• Supports colonization of beneficial strains
• Stabilizes the urogenital microbiota
• Reduces intestinal permeability ("leaky gut") and inflammation
• Supports regeneration of the local mucosa

Composition:

**CFU - colony-forming units