NeuroFast

For painful compressive neuropathies

NeuroFast

NeuroFast is a combination of nucleotides (uridine-5′-monophosphate) and vitamins of the B group, proven effective in painful compressive neuropathies and nerve injuries.

Composition:

Active components
1 capsule (daily dose)
% NRV*
Uridine-5-monophosphate
50 mg
/
Niacin
20 mg
125
Vitamin B6
4,2 mg
300
Thiamin (vitamin B1)
3 mg
273
Folic acid
400 μg
200
Vitamin B12
9 μg
360

*NRV – nutrient reference value

NeuroFast is recommended for:

We recommend NeuroFast to people with peripheral nervous system damage – compressive neuropathy:

  • Carpal, tarsal, cubital tunnel syndrome,
  • Facial nerve paresis,
  • Lumbar syndrome,
  • Lumboschialgia,
  • Lumbocruralgia,
  • Disc herniation (before and after surgery),
  • Cervical syndrome, Cervicobrachial syndrome
  • Nerve injuries of various causes

NeuroFast has the following effects:

  • It promotes regeneration of the damaged nerve
  • It reduces inflammation and neuropathic pain
  • It quickly exhibits an analgesic effect and reduces the use of additional therapeutic options
  • Additionally, it favorably affects cognitive functions (thinking, memory, perception, learning, attention, perception of the environment, logical reasoning)
  • The effectiveness of the components in the therapy of peripheral neuropathies has been confirmed by clinical studies
  • It has a favorable safety profile

Method of use:

Adults: 1 capsule a day with a little liquid, for at least one month continuously

Packaging

10 capsules/30 capsules

Nucleotides

Nucleotides are monomeric structural units composed of a sugar group, attached to one or more phosphate groups, and a nitrogenous base, which can be cytosine, adenine, guanine, thymine or uracil.

Uridine monophosphate

Uridine monophosphate (UMP) is a nucleotide that is important for ribonucleic acid (RNA) synthesis. UMP is resorbed in the intestinal tract via facilitated diffusion and crosses the blood-brain barrier.

Role of UMP in neurons:

  • Participates in the synthesis of RNA
  • It participates in the synthesis of phosphatidylcholine necessary for the formation of biological membranes
  • It promotes neurogenesis, neuronal differentiation and neuroregeneration
  • It stimulates the proliferation, migration and activity of Schwann cells, as well as the secretion of nerve growth factor (NGF) and supports the formation of the myelin sheath, necessary for the transmission of stimuli.
  • It encourages the creation of functional synapses and the transmission of stimuli (synaptic transmission).
  • It affects the reduction of the concentration of fatty acids that are precursors of scar formation (which hinders nerve regeneration)
  • They raise the pain threshold for mechanical and thermal stimuli, prevent the occurrence of allodynia (pain provoked by a non-painful stimulus) on touch
  • It has a positive effect on cognitive functions

Folic acid (vitamin B9)

Folic acid is one of the most important vitamins for human health.
Derivatives of folic acid, folates, are cofactors of many enzymes involved in the synthesis of amino acids, nucleotides, DNA and RNA.

Role of folic acid in neurons:

  • It participates in the biosynthesis of nucleotides, so it has a key role in the synthesis of DNA and RNA
  • It promotes neuro-regeneration
  • It stimulates the proliferation, migration and activity of Schwann cells, as well as the secretion of nerve growth factor (NGF) and supports the formation of the myelin sheath, necessary for the transmission of stimuli.

Vitamin B12 (cyanocobalamin)

Vitamin B12 is a water-soluble vitamin, originating from foods of animal origin – liver, kidneys, milk, meat, eggs, cheese, fish and shellfish.

Role of vitamin B12 in neurons:

  • Production of genetic material RNA and DNA
  • It is essential for the normal functioning of nerve cells and the brain:
  • It has an analgesic effect
  • It participates in the synthesis of the myelin sheath of the axon
  • Participates in the synthesis of neurotransmitters (molecules that transmit electrical signals between neurons and target cells – other neurons, muscle, gland cells

Deficiency of vitamin B12 causes anemia, neuropathy (stiffness, tingling and loss of sensation) and dementia.

Vitamin B6 (pyridoxine)

Vitamin B6 is an essential vitamin, which cannot be synthesized by the body, but must be taken in through food and nutritional supplements.
After absorption, vitamin B6 is transformed into pyridoxal pyrophosphate, which is an important cofactor in multiple metabolic reactions of amino acids, glucose and lipids.

Role of vitamin B6 in neurons:

  • Increases the activity of analgesic neurotransmitters (noradrenaline, serotonin)
  • It improves protein synthesis, which are the structural elements of nerve fibers, fat synthesis and energy metabolism
  • It participates in the synthesis of key neurotransmitters

In adults, neuropathy caused by a lack of vitamin B6 begins with tingling, paresthesias or burning pains in the feet, and then involves the legs and arms by ascending propagation.

Vitamin B1 (thiamine)

Vitamin B1 is present in most plant and animal tissues. It is absorbed in the small intestine by passive diffusion and active transport, and then quickly transformed into thiamine diphosphate (TDP), which is the physiologically active form of vitamin B1.
TDP serves as a basic cofactor in the processes of oxidation (cellular respiration), in the production of adenosine triphosphate (ATP), in the synthesis of glutamate and Y-aminoadipic acid and provides good support in the creation of the myelin sheath.

Role of vitamin B1 in neurons:

  • Suppresses nociceptive and neuropathic pain
  • Improves energy processes in nerve tissue (ATP synthesis), reduces oxidative stress
  • It participates in axonal transport and synaptic transmission

Deficiency of vitamin B1 leads to neuropathy known as beri-beri, which is most often manifested by pain in the extremities and a change in skin color.
Fatigue, irritability and muscle cramps can appear within days or weeks as a result of a lack of this vitamin in the diet.

Vitamin B3 (niacin)

Vitamin B3 is resorbed in the intestines by simple diffusion. Niacin and its derivative nicotinamide (included in the composition of NAD and NADP) are important for the metabolism of carbohydrates, fats, proteins, as well as for the transmission of intracellular signals and DNA repair in cells.

Role of vitamin B3 in neurons:

  • It enables the normal functioning of the nervous system and the maintenance of normal metabolism associated with the delivery of the necessary energy to the nervous tissue

A lack of niacin in the diet can cause nausea, skin and labial lesions, anemia, headache and fatigue. Deficiency of vitamin B3 leads to a disease known as pellagra, which is manifested by the classic clinical triad: dementia, dermatitis and diarrhea.

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